Coeliac Disease, Oats & Avenin – to eat or not?


Avenin is a protein that has a similar chemical structure to the protein, gluten and so some people coeliac disease who react to gluten will also react to avenin.

This article outlines who with coeliac disease the avenin protein affects, what foods it is in and how to find out if you are one of the affected individuals.

bowl of oats with yoghurt (to display a typical breakfast for those with coeliac disease)

What is Avenin?

Avenin is a protein found in oats.

Who does it affect with coeliac disease and why?

In one study, avenin, caused an immune reaction in around 1 in 10 people with coeliac disease (1 ).

The structure of avenin is similar to gluten, which means that those people who’s immune systems react to gluten may also react to avenin.

The the same study, 53% of participants reported having symptoms (bloating, diarrhoea, stomach pain etc) when eating 2 portions of oats/day. But only 8% had an immune response, which is what happens in coeliac disease (1 ).

It is thought that the other 53% are likely to have reacting to the increased fibre in oats.

Although there are many studies looking into a possible reaction to avenin in those with coeliac disease, most are poor quality which means that we can not 100% say that people with coeliac do or do not react to avenin (2 ).

What foods is it in?

As avenin is an oat protein, it would naturally be in any food contain oats.

Be careful not to get mixed up when looking at ‘gluten free’ oats. These oats have been specially manufactured to prevent cross contamination with foods that contain gluten but still contain avenin.

Oats are used as ingredients in many foods such as cereal bars, cereals, breads and cakes. They are used quite commonly in many ‘gluten free’ alternative products as oat flour is useful for baking. Looking at the back of a packet, you will be able to clearly see if a product contains oats as an ingredient – although it will not be in bold like gluten is.

Unfortunately, there are no laws which make manufacturers label when foods ‘may contain’ a certain ingredient through cross contamination.

Should You Avoid Avenin?

It is currently recommended that those with coeliac disease do not need to routinely avoid avenin. This is because the likelihood of you being a ‘reactor’ is so low that it would be of no benefit initially.

It is also thought, that unlike gluten containing foods, that oats actually contain much lower levels of avenin and may be digested much quicker. This means that there is a lower reaction from your immune system.

One study even showed that eating gluten free oats for those with coeliac disease can actually help to improve digestive symptoms (3 ).

In other words, the risk of any harm is so low in comparison to including gluten free oats in your diet which will provide you with a good source of fibre.

You may find that gluten free oats give you symptoms due to the increased fibre. As a cheaper option than ‘gluten free’ breakfast cereals, many people opt for gluten free oats in their breakfast when perhaps they used to have a much lower fibre breakfast. This sudden changes can something cause symptoms but has nothing to do with the avenin or immune system.

Although avoiding gluten free oats is not routinely recommended, for the reasons above, it is still your decision to make. If you feel that after being informed of the risks and benefits, that you would rather avoid oats, then do so as it is your body.

Bottom Line

Avenin is a protein found in oats. A small number of people with coeliac disease may react to avenin, however, do not cut it out of your diet until you have been advised to do so by a registered dietitian as you may not need to and it would be unfortunate to unnecessarily avoid a food.


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